Danielle George - All Headline News Staff Reporter
Davis, California (AHN) - A tamoxifen-like drug developed by UC Davis and
Finnish researchers may help to prevent breast cancer according to a preliminary
study.
These reports indicate that prevention of breast cancer may be another
benefit of the use of ospemifine, says Michael W. DeGregorio, a professor
of medicine at UC Davis. The findings are very encouraging.
DeGregorio is senior author of the November article and a contributing author
of the December paper. He has spent the last 20 years developing ospemifene
in collaboration with Risto Lammintausta, managing director of Hormos Medical
Corp. in Turku, Finland.
In the Journal of Steroid Biochemistry and Molecular Biology, DeGregorio
and his colleagues found that mice in the ospemifene group were 95 percent
less likely than mice in the control group to develop breast cancer. The
study is available online in advance of its publication in print at
www.sciencedirect.com
Sometimes it seems that every magazine, newspaper, radio show, and piece
of mail has a headline declaring that every womans risk of developing
breast cancer is increasing. There is a numbing feeling of inevitability
in these pronouncements. More and more women think about breast cancer as
a when rather than an if.
Its true that theres more breast cancer now than ever before,
that between 1979 and 1986 the incidence of invasive breast cancer in the
United States increased 29 percent among white women and 41 percent among
black women, and incidence of all breast cancers doubled. Its true
that the percentage of women dying from breast cancer has remained virtually
unchanged over the past 50 years, and that every 12 minutes throughout the
last half of the 20th Century another woman died of breast cancer. And its
true that breast cancer is the disease that women fear more than any other,
that breast cancer is the biggest killer of all women aged 35 to 54, and
that of the 2.5 million women currently diagnosed with breast cancer, half
will be dead within ten years.
These facts frighten me, and they also make me angry. My studies spanning
25 years and many disciplines have convinced me that the majority of breast
cancers are causally related to the high levels of radiation and chemicals
released into our air, water, soil, and food over the past 50 years. United
States government researchers estimate that 80 percent of all cancers are
environmentally linked.
What can be done? The answer isnt as simple as a yearly mammogram.
That may help detect breast cancer, but it wont prevent it. To prevent
breast cancer we need to take individual and collective action.
Effective action requires understanding the causes of breast cancer and what
decreases breast cancer risk. But there are few conclusive answers to these
queries, partly because most research focuses on eliminating breast cancer
after - not before - it occurs. Science has validated so few risk factors
for breast cancer that 70 percent of the women diagnosed with breast cancer
have no identifiable risk factors.
Unfortunately, our sex, age, reproductive history, family history, exposure
to radiation (such as fallout from above-ground atomic bomb tests), race,
culture, and height are beyond our control. When were told these are
the only risk factors, we can be left with feelings of hopelessness and panic.
But when we include risk factors that are considered not well
substantiated - but which are clearly contributing to breast cancer
incidence - including ingestion of and exposure to prescription hormones,
hormone-mimicking organochlorines, prescription drugs, petrochemicals, and
electromagnetic fields, as well as unwise lifestyle choices such as smoking
tobacco, drinking alcohol immoderately, wearing a bra, or not exercising,
then we can find many ways to lower breast cancer risk. No need to panic.
We can help prevent breast cancer on an individual basis by buying organically
grown food, filtering our water, building powerful immunity, living wisely
and vigorously, being in touch with our breasts, using natural remedies for
menopausal problems, and by paying attention to our Wise Healer Within.
But theres a limit to the control that any one woman has over her exposure
to petrochemicals, radiation, and other environmental cancer-inciters. Limiting
the production and discharge of substances that initiate and promote cancer
is collective work. When our individual acts are combined with the acts of
others, we can achieve the envisioned social change. For example, as I saw
more and more evidence that chlorine residues from papermaking contribute
to breast cancer, I began to ask for chlorine-free paper from my book printer.
They went from amazement and puzzlement at my request to contracting with
a new paper supplier who can provide them with elemental chlorine-free paper.
(Im not the only one asking, you see.)
Whether you think your risk of breast cancer is high, low, or average, there
are things you can do, individually and with others, to help yourself stay
free of breast cancer and to help stop the epidemic of breast cancer too.
(What is your risk of breast cancer? See Risk Assessment, page
317 of Breast Cancer? Breast Health! the Wise Woman Way to educate
your guess.)
Since 1950 the incidence of breast cancer in the U.S. has increased by
53 percent, according to Nancy Brinker, chair of President Clintons
Special Commission on Breast Cancer.
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