PARIS (AP) - Experiments on mice have shown promise for the future of
nanotechnology in treating cancer.
The research brings doctors one step closer to being able to inject patients
with nanoparticles that bore inside tumours and release powerful doses of
cancer-killing drugs while leaving the rest of the body unscathed.
After seeing how the mice were cured of human prostate cancer with the
technology, cancer specialists gathered at the European Cancer Conference
in Paris on Tuesday praised the work as impressive and said they had high
hopes for its application to patients.
"There are a lot of candidates for intelligent carriers, and these nanoparticles
are among them," said Dr. Gordon McVie, a professor at the European Institute
of Oncology in Milan, Italy, who was not involved with the research.
"This is a new system, and the more systems we have, the better, because
we'll probably be lucky if we get one system to work out of 10," McVie said.
"It looks as if it could be quite good."
Dr. David Kerr, a professor of clinical pharmacology and cancer therapeutics
at Oxford University in England who was not connected with the research,
said the latest approach outlined at the conference may have the edge over
others.
Previous designs of nanoparticles have used antibodies to zone in on cancer
cells.
"The body's immunodefence system can create antibodies to the therapeutic
antibodies, deactivate them and prevent the antibody binding to the right
cancer cells. This looks like a step forward," Kerr said.
Nanotechnology is the science of manipulating matter smaller than 100 nanometres
and taking advantage of properties that are present only at that level, such
as conductivity. A nanometre is one-billionth of a metre, or about one-millionth
the size of a pin head. The prefix comes from "nanos," the Greek word for
dwarf.
Nanotech has been around for several decades, but only now is its potential
starting to be realized. Medicine is expected to be one of the fields to
benefit most from the technology. In cancer, it is hoped the technology will
allow for more precisely targeted drugs and surgery and less toxic chemotherapy.
The study, conducted by scientists at Harvard Medical School and the
Massachusetts Institute of Technology, which are pioneering cancer
nanotechnology, involved engineering nanoparticles embedded with the cancer
drug Taxotere. The particles were then injected directly into human tumours
created from prostate cancer cell lines and implanted into the flanks of
mice. The mice were watched for 100 days.
The technology being tested involves a nanoparticle made of a hydrogen and
carbon polymer with bits of drug bound up in its fabric and attached to a
chemical that hones in on cancer cells. The polymer gradually dissolves,
exposing the nuggets of drug little by little.
The mice were divided into five groups, including one that had their tumours
injected with ineffective saltwater. A second group died after injections
of a nanoparticle containing no drugs.
Colon Cancer Centre
Medical Tourism Saves You Money, but Which Country is Best?
Increasingly, people from the industrialized countries of the world are seeking
out places where they can both enjoy a vacation and obtain medical treatment
at a lower price, than in their country of residence.
Medical tourists are increasing in numbers, but which country is best for
medical tourism?
Medical Tours to India
For medical tourism, India is a relative newcomer, but recent estimates indicate
that the number of foreign patients is increasing by 30 percent each year.
India has world-class medical facilities, with excellent staff in all areas
of medical care. All Indian hospitals are equipped with the latest electronic
and medical diagnostic equipment.
India also has the technological sophistication and infrastructure to maintain
its market lead. Indian pharmaceuticals for example, meet the stringent
requirements of the U.S. Food and Drug Administration.
India's quality of care is world class, competing with any other industrialized
country.
Indian medical centres provide services that are in fact uncommon elsewhere.
For example, hip surgery patients in India can have a hip-resurfacing procedure,
in which damaged bone is taken away and replaced with chrome alloy, an operation
that costs less and causes fewer traumas than the traditional replacement
operations carried out in western countries.
Medical Tours to South East Asia
South East Asia offers some great advantages for medical tourism with Thailand
being the main destination and the main rival to India.
The Thai medical profession is probably the most advanced in the region and
successive governments have invested in ensuring the necessary education
and training.
Many doctors undertake specialist training abroad, particularly in the United
States and Europe and are at least as well qualified as physicians in these
countries.
Singapore and Malaysia also have well developed medical facilities.
Medical Tours to the East Indies
For North American patients, the East Indies and Costa Rica in particular,
are the chosen destinations for medical tourism.
Costa Rica provides close, inexpensive, high-quality medical care without
a trans-Pacific flight. Cost wise though, it is more expensive for medical
tourists generally, particularly from destinations outside of the USA.
Medical Tourism in South America
Medical tourism in South America is mainly cantered on Brazil, which has
been a centre for plastic surgery for many years.
With a large influx of medical tourists particularly from the USA, Brazil
has built a well-developed healthcare industry in all areas.
Although slightly more pricey than many other destinations, you are assured
of good quality healthcare in Brazil - one of the most beautiful countries
on earth.
Argentina also has a flourishing medical tourism industry, but its geographical
position is a problem for many.
The Rest
Medical tourism is growing in other countries with Eastern Europe, Africa,
and Dubai entering the industry.
Dubai will be providing the Dubai Healthcare City by 2010 and this clinic
will be the largest international medical centre between Europe and South
East Asia. Including a new branch of the Harvard Medical School, it will
be prestigious, but aimed at the medical tourist with more money.
Eastern Europe and Africa are emerging markets, but probably have some way
to go to match the healthcare services available in countries such as India.
India for Medical Tourism
There are many choices for medical tourists seeking overseas healthcare and
many destinations have reasons to recommend them, but overall for medical
tourists, it will be India that will be the most attractive. Why? Simply,
India has wide variety of treatments, world-class hospitals, and medical
staff, is inexpensive, and offers a beautiful holiday destination.
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