SAN DIEGO , Oct. 27 /PRNewswire-FirstCall/ -- Halozyme Therapeutics, Inc.
(Amex: HTI), a biopharmaceutical company focused on the development and
commercialization of recombinant human enzymes, today announced it has initiated
patient enrollment for its Chemophase(TM) Phase I clinical trial and has
dosed two patients. Chemophase is a novel recombinant therapeutic being developed
to enhance the delivery of chemotherapy.
The initial clinical protocol for Chemophase is designed to evaluate a single
intravesical (into the bladder) administration of Chemophase along with the
widely used anticancer drug mitomycin in patients with superficial bladder
cancer. The Phase I study will enroll at least five evaluable patients with
superficial bladder cancer. The objectives of the study are to determine
the safety, tolerability and pharmacokinetics of Chemophase administered
intravesically with mitomycin. The study is being conducted at BCG Oncology
in Phoenix , Arizona under the supervision of Donald L. Lamm, MD, the principal
investigator.
National Cancer Institute
Cancer Diagnosis: Strategies for Getting the Best Treatment
As a patient with cancer, two of the most important decisions you will make
are which treatment you will receive and where.
But diagnosing cancer is a very complex process that involves many health
care professionals. In addition, the testing that is done on patients varies
between doctors and specialists. And even the best health care professionals
make mistakes.
How do newly diagnosed patients know they are getting the best therapy for
their cancer?
Unfortunately, most patients dont get the best treatment because they
are diagnosed by a doctor who is not an oncologist. Therefore, that doctor
is not likely to direct them to the most up-to-date therapies available.
The first step toward getting what you need is to get a second opinion. The
Institute for Advanced Study in Medicine reported that 25% of patients had
their treatment changed based on a second opinion.
Comprehensive Cancer Centers are the best places to get second opinions.
Thats where the experts are, doctors who think about your type of cancer
every day. And thats what you want.
If you arent near a National Cancer Institute-Designated Comprehensive
Cancer Center or Clinical Cancer Center (you can find their locations online),
you can still get a second opinion. Choose a doctor who is not affiliated
with your doctor, and who is at a hospital that is not affiliated with your
doctors hospital.
Another important part of getting the best therapy is to get a second opinion
on your cancer by an expert pathologist. This involves getting the biopsy
specimen to an outside pathologist.
Pathologists cant always precisely determine the stage of cancer, and
sometimes not even the type of cancer. And, sometimes tests that could be
done on your biopsy specimen arent, simply because they arent
commonly used. But that doesnt mean these tests wont help you.
You need an expert to examine your biopsy specimens. For example, The Armed
Forces Institute of Pathology has an excellent reputation in pathology.
Another important thing to do when you are first diagnosed is to contact
the organizations for your type of cancer. They can lead you to experts in
that field. Finally, get good nutritional counseling, and if you smoke cigarettes
or drink alcohol, try your best to stop.
Ms. Walter is a long-time patient advocate who supports the rights of cancer
patients to make informed choices about every aspect of their treatment and
care. Her goal is to educate patients about their full range of options and
give them every possible tool to live a long, high-quality life. A member
of the American Medical Writers Association, Ms. Walter has worked in the
publishing field for 25 years, the last 12 years in medical publishing. She
has also worked in the medical communications field and in the pharmaceutical
industry.
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