2005 OCT 25 - (NewsRx.com) -- Researchers called for further clinical trials
to standardize care for gastric cancer patients.
According to a study from Australia, "Gastric cancer has a poor prognosis.
The majority of patients will relapse after definitive surgery, and 5-year
survival after surgery remains poor.".
"The role of adjuvant therapy in gastric cancer has been controversial given
the lack of significant survival benefit in many randomized studies so far.
The results of a large North American study (Gastrointestinal Cancer Intergroup
Trial INT 0116) reported that postoperative chemoradiotherapy conferred a
survival advantage compared with surgery alone, which has led to the regimen
being adopted as a new standard of care," explained L. Lim and colleagues,
Peter MacCallum Cancer Center.
The experience of sunburn can be a very efficient (i.e. painful) reminder
to heed adequate protection on future occasions. However more importantly,
it should be a reminder of the long-term effects of sun exposure on our bodies
and health which can include aging of the skin and skin cancer.
In order to more fully understand these consequences, lets take a look
at exactly what sunburn is, its symptoms and its effect on the body.
Sunburn results when the amount of exposure to the sun, or other ultraviolet
light source (e.g. tanning lamps and welding arcs etc.), exceeds the ability
of the body's protective pigment, melanin, to protect the skin. Melanin content
varies greatly, but in general darker skinned people have more melanin than
lighter skinned. (Although fairer skinned people are generally more prone
to getting sunburn than darker skinned people, this certainly does not exclude
the latter from risk.)
Sunburn destroys cells in the outer layer of the skin, damaging tiny blood
vessels underneath. Burns deeper into the skins layers also damage
elastic fibers in the skin, which over time and with repeated sun overexposure,
can result in the appearance of yellowish, wrinkled skin.
The damage to skin cells from UV exposure (either sunlight or tanning lamps
etc.) can also include damage to their DNA. Its this repeated DNA damage,
which can lead to a cell becoming cancerous. With the incidence of skin cancer
rising dangerously in many parts of the world, and with its ability to develop
and establish itself in the body long before external signs are
detected, -- paying attention to this aspect of sun exposure and sunburn
should certainly not be ignored if we are serious about preserving our health.
Now while it may be easier to ignore the effects of sunburn occurring at
a cellular level, ignoring the external symptoms of sunburn in the days
immediately following such exposure is entirely another matter.
While sunburn is usually not immediately obvious, skin discoloration (ranging
from slightly pink to severely red or even purplish) will initially appear
from 1 24 hours after exposure. Although pain is usually worst 6
48 hours afterward, the burn can continue to develop for 24 72 hours
after the incident. Where there is skin peeling, this generally occurs 3
8 days after the burn occurs.
While minor sunburns typically cause nothing more than warm/hot skin, slight
redness, and tenderness to the affected area, -- in more serious cases, extreme
redness, swelling and blistering can occur. These blisters filled with fluid
may itch and eventually break. This can then cause peeling of the skin, exposing
an even tenderer layer of skin underneath.
Severe sunburn can cause very red, blistered skin but can also be accompanied
by fever, chills, nausea (in some cases vomiting), and dehydration. In instances
of extreme sunburn where the pain is debilitating, medical treatment may
be required.
While the immediate effects of sunburn can certainly be painful and cause
discomfort, the real deterrent to UV overexposure should be the potential
damage to your long-term health including the risk of premature aging
of the skin along with skin cancer.
Dont let sunburn and sun overexposure kill your chances of enjoying
youthful skin, and a healthy body. Remember, the easiest way to treat sunburn
will always be to avoid it in the first place!
Angela Perin is author of the comprehensive new guide
"Your
Personal Guide to Tanning" - covering everything from your skin, uv light
& sun-tanning, to sunburn, skin cancer, sunburn, sun protection and sunless
tanning. Discover Safe
Tan - The Ultimate Experience in Natural Sunless Tanning and download
your free copy of this guide including bonus homemade recipes for sunburn
relief, sunscreen and exfoliation!
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